Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones

Rafael Martin Romero (1) , Neethu Thyagarajan (1) , Nora Hellou (1) , Clément Chauvier (1) , Timothé Godou (1) , Lucile Anthore-Dalion (1) , Thibault Cantat (1)

1 LCMCE - Laboratoire de Chimie Moléculaire et de Catalyse pour l'Energie (ex LCCEF)

A transfer hydrosilylation of ketones employing silyl formates as hydrosilane surrogates under mild conditions is presented. A total of 24 examples of ketones have been successfully converted to their corresponding silyl ethers with 61–99% yields in the presence of a PNHP-based ruthenium catalyst and silyl formate reagent. The crucial role of the ligand for the transformation is demonstrated.

Domaines: Catalyse; Chimie organique

Rafael Martin Romero, Neethu Thyagarajan, Nora Hellou, Clément Chauvier, Timothé Godou, et al.. Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones. Chemical Communications, 2022, 58 (43), pp.6308-6311. ⟨10.1039/D2CC00666A⟩. ⟨cea-03662659⟩