Design, synthesis and biological evaluation of inhibitors of cathepsin K on dedifferentiated chondrocytes

Xiao-Yu Yuan , Zhongyuan Ren (1) , Yuqing Wu (2) , Carole Bougault (3) , Leyre Brizuela (3) , David Magne (3) , Rene Ren (3) , Saïda Mebarek (3)

1 CSAP - Chimie Supramoléculaire Appliquée
2 State Key Laboratory of Supramolecular Structure and Materials
3 MEM² - Métabolisme, Enzymes et Mécanismes Moléculaires

Domains: Biochemistry, Molecular Biology

Xiao-Yu Yuan, Zhongyuan Ren, Yuqing Wu, Carole Bougault, Leyre Brizuela, et al.. Design, synthesis and biological evaluation of inhibitors of cathepsin K on dedifferentiated chondrocytes. Bioorganic and Medicinal Chemistry, 2019, 27 (6), pp.1034-1042. ⟨10.1016/j.bmc.2019.02.003⟩. ⟨hal-02132744⟩