MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering

Ricardo Andrade (1, 2, 3) , Mahdi Doostmohammadi (4, 5) , João Santos (6) , Marie-France Sagot (7, 1) , Nuno P Mira (6) , Susana Vinga (5, 8)

1 ERABLE - Equipe de recherche européenne en algorithmique et biologie formelle et expérimentale
2 PEGASE - Département PEGASE [LBBE]
3 IME - Instituto de Matemática e Estatística
4 School of Mathematics - University of Edinburgh
5 IDMEC - Instituto de Engenharia Mecânica [Lisboa]
6 Institute for Bioengineering and Bioscience, Instituto Superior Técnico
7 Baobab
8 INESC-ID - Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa

Keywords: Optimization; Metabolic Engineering; Systems Biology

Domains: Quantitative Methods [q-bio.QM]; Bioinformatics [q-bio.QM]

Ricardo Andrade, Mahdi Doostmohammadi, João Santos, Marie-France Sagot, Nuno P Mira, et al.. MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering. BMC Bioinformatics, 2020, 21 (1), pp.1-13. ⟨10.1186/s12859-020-3377-1⟩. ⟨hal-02490353⟩